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AL

Alnylam Pharmaceuticals, Inc.

ALNYHealthcareNASDAQ

Biotechnology

PriceMA150MA200
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Indicator snapshot
MA150-19.03%
$364.94

Price below medium-term moving average.

MA200-23.77%
$387.65

Below long-term trend line.

RSI-14neutral
45.5

Balanced. Not overbought, not oversold.

MACDpositive
+1.4189

Histogram positive — upward momentum.

Financials · Annual
Revenue
$3.71B
+65.2% YoY
Net Income
$313.7M
+212.8% YoY
EBITDA
$631.4M
+453.1% YoY
Free Cash Flow
$204.7M

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Daily timeframe
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About Alnylam Pharmaceuticals, Inc.

Headquartered within the healthcare sector, Alnylam Pharmaceuticals, Inc. focuses on Biotechnology services and products. Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic acid interference in the United States, Europe, and internationally. At a $39.45B market cap, Alnylam Pharmaceuticals, Inc. ranks as a large-cap company within healthcare. The company offers ONPATTRO for hereditary transthyretin-mediated (hATTR) amyloidosis; AMVUTTRA for ATTR and hATTR amyloidosis; Leqvio for hypercholesterolemia; Qfitlia for hemophilia A or B; GIVLAARI for acute hepatic porphyria; and OXLUMO for primary hyperoxaluria type 1.

Key stats
Market Cap$39.45B
P/E (TTM)74.06
Fwd P/E21.15
EPS$3.99
Beta0.30
52W Change+3.5%
ROE90.4%
Analysis

With $3.01B in cash and $2.97B in debt, ALNY maintains more liquidity than leverage. This favorable balance sheet position can be an asset when capital markets become less accommodating. Free cash flow comes in at $204.7M, providing flexibility for reinvestment, buybacks, or dividends. Consistent free cash flow generation is often considered a sign of operational health. ROE of 90.4% points to exceptionally high capital efficiency, indicating how much profit the company produces per dollar of shareholder equity. Return on assets of 10.1% further supports the picture of efficient asset utilization. Revenue has grown from $1.04B (2022) to $3.71B (2025), reflecting a 258% increase over the period.

With a beta below 0.7, Alnylam Pharmaceuticals, Inc. typically sees smaller price swings than the overall market, offering a degree of stability during turbulent periods. At over 50x earnings, ALNY carries valuation risk — any slowdown in growth expectations could lead to meaningful price adjustments. Understanding these risk dimensions helps frame what to watch going forward as conditions evolve for Alnylam Pharmaceuticals, Inc. and its sector.

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