OPKO Health, Inc.
OPKHealthcareNASDAQDiagnostics & Research · Last scanned Jun 3, 2026
Scan Results
Daily timeframeOPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The $1.06B market capitalization puts OPK squarely in small-cap range for its industry. The company operates in two segments, Pharmaceutical and Diagnostics.
Market Cap
$1.06B
Beta
1.41
P/E (TTM)
—
P/E (Fwd)
-4.38
EPS (TTM)
$-0.27
EPS (Fwd)
$-0.32
ROE
-16.9%
ROA
-6.4%
Cash
$331.9M
Total Debt
$396.9M
Free CF
-$36.1M
52W Change
3.7%
Annual Financials
Cash vs Debt
On the balance sheet, OPK has $331.9M in cash with $396.9M in obligations. The ability to service this debt comfortably depends on continued operational cash generation. Free cash flow is running at -$36.1M, which bears watching. Negative free cash flow can be acceptable during heavy investment periods but needs to improve over time. ROE of -16.9% points to negative capital efficiency, indicating how much profit the company produces per dollar of shareholder equity. Revenue has pulled back from $1.00B (2022) to $606.9M (2025), a 40% decline worth watching.
Negative free cash flow means the company is currently spending more than it generates, which may require future fundraising or debt if the trend continues. No single metric tells the full story. Reviewing OPK's risk profile alongside its fundamentals and technical indicators provides a more complete picture.